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  • Integrative Biotechnology

Faculty - Integrative Biotechnology

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LEE, SUK CHAN 사진 more
  • Professor
  • LEE, SUK CHAN 홈페이지 바로가기

[Research Interest]

KWEON, DAE HYUK 사진 more
  • Professor
  • KWEON, DAE HYUK 홈페이지 바로가기

[Research Interest]

Development of chemical regulators of SNARE-driven membrane fusion, and development of Botox substitutes for cosmetic and therapeutic purposes. Development of nanoperforators of viral envelope for antivirals (e.g., anti-influenza drugs) Protein engineering of industrial enzymes for improved stability, solubility and activity Recombinant protein production technologies (protein expression control, purification, refolding and protein characterization through spectroscopies)

YOON, KEEJUNG 사진 more
  • Professor
  • YOON, KEEJUNG 홈페이지 바로가기

[Research Interest]

Regulation of neural stem cells and brain development Stem cell therapy using induced pluripotent stem cells Neuropathology of brain infections and cancers

CHO, JAE YOUL 사진 more
  • Professor
  • CHO, JAE YOUL 홈페이지 바로가기

[Research Interest]

OH, JEONG SU 사진 more
  • Associate Professor Development and Reproduction
  • OH, JEONG SU 홈페이지 바로가기

[Research Interest]

Regulation of meiotic cell cycle: Cell division is a highly regulated process, driven by the action of cyclin-dependent kinases (Cdks) and their regulatory subunits, cyclins. Inappropriate activation of Cdk/cyclin complexes can drive unregulated cell division resulting in cell death or tumor formation. Cdk/cyclin complexes also play essential roles in a variety of cellular processes such as development and differentiation. Our lab is focused on the action of Cdk/cyclin complexes and all pathways that control or are controlled by Cdk/cyclin complexes during female meiosis. Homologous chromosome segregation and aneuploidy: Reduction of chromosome number during meiosis is essential for producing haploid gametes from diploid parental cells. This reduction is achieved by two successive rounds of chromosome segregation, meiosis I (MI) and meiosis II (MII), after a single round of DNA replication. Although MII resembles mitosis in that sister chromatids separate and segregate to different daughter cells, the pattern of chromosome segregation during MI is unique. During MI, homologous chromosomes pair and then segregate from each other. Defects in this process result in aneuploidy, leading to miscarriages, infertility and genetic disorders such as Down’s syndrome. Therefore, our lab studies the molecular mechanisms that control homologous chromosome segregation during meiosis. Control of oocyte quality: Mammalian oocytes are arrested at the prophase of the first meiosis. After LH surge, the oocytes resume meiosis. During these processes, the oocytes is subjected to various sources of damage-inducing factors, which may lead to a progressive deterioration of oocyte quality. Thus, the control of oocyte quality is critical to reproductive success and survival of a species; however, the precise mechanisms underlying this process remain elusive. Our lab is interesting in identifying the molecular mechanisms that control oocyte quality and eventually leading to identification of diagnostic markers that are predictive of oocyte quality in a clinical setting. Chromatin remodeling during fertilization: Fertilization leads to the transformation of two haploid gametes into a totipotent zygote. During this process, highly condensed chromatins are largely reorganized, preparing to initiate the transcription of embryonic genes which are essential for obtaining the pluripotency. Our lab is exploring the mechanisms of the chromatin remodeling upon fertilization and investigating the role of maternal factors in this process.

CHUNG, WOO JAE 사진 more
  • Associate Professor Biomaterials
  • CHUNG, WOO JAE 홈페이지 바로가기

[Research Interest]

Phage/peptide-based biomaterials Biomimetic materials Bioprinting Therapeutic bionanomaterials

LEE, JONG SUNG 사진 more
  • Associate Professor Cell Biology(Dermatology)
  • LEE, JONG SUNG 홈페이지 바로가기

[Research Interest]

SONG, MINKYUNG 사진 more
  • Assistant Professor T cell biology and tumor immunology
  • SONG, MINKYUNG

[Research Interest]

Investigation of transcriptional, epigenetic and metabolic regulatory mechanisms of T cell function in diverse disease settings Exploring the specific role of the ER for sensing microenvironmental conditions and controlling cellular responses Devising novel strategies for cancer treatment

JEON, YOUNG-JUN 사진 more
  • Assistant Professor
  • JEON, YOUNG-JUN

[Research Interest]

A. Liquid Biopsy / Circulating Tumor Nucleic Acids / Next Generation Sequencing / Bioinformatics B. Cancer Recurrence / Drug Resistance / Radiation Resistance C. Cancer Cell Biology / Metabolic Stresses / ERAD D. Non-codingRNAs