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  • Pharmacy

Faculty

  • Professor
  • LEE, JEONGMI 홈페이지 바로가기

Research Interest

Discovery of biomarkers and understanding of molecular mechanisms of diseases and drugs through metabolomics-based studies
Chromatography-based analysis of endogenous and exogenous small molecules (metabolites, drugs, and biologically active substances) in various types of matrices 
Development/design of green solvents (deep eutectic solvents) and their applications 
Statistics-based design of experiment (DoE) for efficient experiment performance
Development of green sample preparation methods

Journal Articles

  • (2024)  Green and efficient method to acquire high-value phycobiliprotein from microalgal biomass involving deep eutectic solvent-based ultrasound-assisted extraction.  FOOD CHEMISTRY.  449,  1
  • (2024)  Fabrication of chitin-glucan nanofibers: Insights into mushroom pretreatment and subsequent acidic deep eutectic solvent-based esterification.  CARBOHYDRATE POLYMERS.  323,  121391
  • (2022)  Ecofriendly and enhanced biogenic synthesis of silver nanoparticles using deep eutectic solvent-based green tea extracts.  JOURNAL OF CLEANER PRODUCTION.  379,  134655
  • (2021)  Insights into the enhanced thermal stability of lysozyme with altered structure and activity induced by choline chloride-based deep eutectic solvents containing polyols and sugars.  JOURNAL OF MOLECULAR LIQUIDS.  349,  118143
  • (2021)  Carvone and its eutectic mixtures as novel, biodegradable, and tunable solvents to extract hydrophobic compounds in substitution for volatile toxic solvents.  FOOD CHEMISTRY.  374,  131630
  • (2021)  A solvent-free headspace GC/MS method for sensitive screening of N-nitrosodimethylamine in drug products.  ANALYTICAL METHODS.  13,  30
  • (2021)  Preparation and characterization of various chitin-glucan complexes derived from white button mushroom using a deep eutectic solvent-based ecofriendly method.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.  169,  00
  • (2021)  Toxico-metabolomics study of a deep eutectic solvent comprising choline chloride and urea suggests in vivo toxicity involving oxidative stress and ammonia stress.  GREEN CHEMISTRY.  23,  3
  • (2020)  Applications of deep eutectic solvents to quantitative analyses of pharmaceuticals and pesticides in various matrices: a brief review.  ARCHIVES OF PHARMACAL RESEARCH.  43,  9
  • (2020)  Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance.  BIOMATERIALS.  262, 
  • (2020)  Insights into the Vastly Different Effects of Eutectic Solvents on the Stability of Phenolic Compounds.  JOURNAL OF PHYSICAL CHEMISTRY LETTERS.  11,  13
  • (2020)  In situ situ formation of thymol-based hydrophobic deep eutectic solvents: Application to antibiotics analysis in surface water based on liquid-liquid microextraction followed by liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A.  1614,  -
  • (2020)  Mixing of menthol-based hydrophobic deep eutectic solvents as a novel method to tune their properties.  JOURNAL OF MOLECULAR LIQUIDS.  301,  -
  • (2020)  Systematic investigation of the extractive desulfurization of fuel using deep eutectic solvents from multifarious aspects.  FUEL.  264,  1
  • (2019)  Headspace conditions and ingredients can affect artefactual benzene formation in beverages.  FOOD CHEMISTRY.  293,  1
  • (2019)  Hydrophobic deep eutectic solvents for the extraction of organic and inorganic analytes from aqueous environments.  TRAC-TRENDS IN ANALYTICAL CHEMISTRY.  118,  1
  • (2019)  An HPLC-UV-based quantitative analytical method for Chrysanthemum morifolium: Development, validation, and application.  Analytical Science and Technology.  32,  4
  • (2019)  Application of Deep Eutectic Solvents to Prepare Mixture Extracts of Three Long-Lived Trees with Maximized Skin-Related Bioactivities.  APPLIED SCIENCES-BASEL.  9,  13
  • (2019)  Establishment and validation of an analytical method for quality control of health functional foods derived from Agastache rugosa.  Analytical Science and Technology.  32,  3
  • (2019)  A comprehensive metabolomics investigation of hippocampus, serum, and feces affected by chronic fluoxetine treatment using the chronic unpredictable mild stress mouse model of depression.  SCIENTIFIC REPORTS.  9,  1

Publications

  • (2015)  핵심 의약품분석학.  신일북스.  Co-author
  • (2015)  약물작용 기초이론.  군자출판사.  Co-author

Conference Paper

  • (2021)  Unravelling the in vitro and in vivo toxicity of deep eutectic solvents consisting of safe compounds including choline chloride.  2nd International Meeting on Deep Eutectic Systems.  PORTUGAL
  • (2020)  Metabolomic investigation of sex-specific depression in plasma and whole brain of the sub-chronic variable stress mouse model.  23rd Annual Meeting of the Korean Society for Brain and Neural Sciences.  KOREA, REPUBLIC OF
  • (2020)  Advanced biogenic synthesis of silver nanoparticles using deep eutectic solvents-based plant extracts.  2020 Fall International Convention of the Pharmaceutical Society of Korea.  KOREA, REPUBLIC OF
  • (2020)  Investigation of carvone and its eutectic mixtures as novel extraction solvents with tunable properties.  2020 Fall International Convention of the Pharmaceutical Society of Korea.  KOREA, REPUBLIC OF
  • (2020)  Discovery of biomarkers in plasma and whole brain of sex-specific depression based on non-targeted metabolomics study.  The 28th Annual Meeting of the Korean Society of Applied Pharmacology.  KOREA, REPUBLIC OF
  • (2020)  Green and simple sample preparation method for trace analysis of fluoroquinolone antibiotics in surface water.  제64회 한국분석과학회 하계 학술대회.  KOREA, REPUBLIC OF
  • (2020)  Separation of chitin-glucan complex from white button mushroom (Agaricus bisporus) using deep eutectic solvents.  제64회 한국분석과학회 하계 학술대회.  KOREA, REPUBLIC OF
  • (2020)  Toxicity assessment based on non-targeted metabolomics study of natural deep eutectic solvents in in vivo mice.  제64회 한국분석과학회 하계 학술대회.  KOREA, REPUBLIC OF
  • (2019)  Benzene monitoring in beverages: revisiting analysis conditions and ingredients.  제63회 한국분석과학회 추계 학술대회.  KOREA, REPUBLIC OF
  • (2019)  Investigation of the effects of choline- and betaine- based natural deep eutectic solvents on the structure, stability and activity of lysozyme.  제63회 한국분석과학회 추계 학술대회.  KOREA, REPUBLIC OF
  • (2019)  Non-targeted metabolomics study of toxicity of natural deep eutectic solvents in in vitro cell lines and in vivo rats.  제63회 한국분석과학회 추계 학술대회.  KOREA, REPUBLIC OF
  • (2019)  In situ formed thymol-based deep eutectic solvents coupled with liquid-liquid microextraction toward simple and green sample preparation for antibiotics in surface water.  2019 Fall International Convention of the Pharmaceutical Society of Korea.  KOREA, REPUBLIC OF
  • (2019)  New approach to expanding the applicability of hydrophobic deep eutectic solvents by mixing: evaluation of their extraction capability and coverage in comparison with conventional organic extraction solvents.  2019 Fall International Convention of the Pharmaceutical Society of Korea.  KOREA, REPUBLIC OF
  • (2019)  Extractive Desulfurization with Ammonium-based Deep Eutectic Solvents: Systematic and Multifarious Consideration for the Optimal Solvent Selection.  1st International Meeting on Deep Eutectic Systems.  PORTUGAL
  • (2019)  The effects and mechanisms of deep eutectic solvents on the stability of (-)-epigallocatechin gallate.  1st International Meeting on Deep Eutectic Systems.  PORTUGAL
  • (2019)  Mixtures of menthol-based hydrophobic deep eutectic solvents: application as green solvents to extract bioactive compounds from Ginkgo biloba leaves.  제62회 한국분석과학회 춘계학술대회.  KOREA, REPUBLIC OF
  • (2019)  Investigation of the effects of different brewing conditions on Camellia sinensis infusions.  제62회 한국분석과학회 춘계학술대회.  KOREA, REPUBLIC OF
  • (2019)  Deep eutectic solvents: Green alternatives to toxic organic solvents.  2019 환경독성보건학회/환경분석학회 춘계연합학술대회.  KOREA, REPUBLIC OF
  • (2018)  Investigation of stabilization/destabilization effects and mechanisms of solvents on epigallocatechin gallate.  제61회 한국분석과학회 추계학술대회.  KOREA, REPUBLIC OF
  • (2018)  Investigation of the effects of different brewing conditions on Camellia sinensis infusions.  제61회 한국분석과학회 추계 학술대회.  KOREA, REPUBLIC OF