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ABOUT SAINT

Professors

  • Associate Professor
  • KIM, YONGHO 홈페이지 바로가기

Research Interest

Part. 1 Protein-based materials: Non-biodegradable, conductive and bio-compatible protein-based gel / Extracellular matrix-mimetic protein-based environment / Controlling gel properties for biosensor and drug delivery, Part. 2 Supramolecular self-assembly: Coiled-coil based self-assemble supramolecule modularization / Protein-directed self-assembly of a fullerene crystal, Part. 3 Cell behavior control using protein: Multi-functional Mussel Adhesive Protein (MAP) library / Regulating cell activity and morphology using functional proteins

Education

  • (PhD) University of Pennsylvania In Chemistry (2005-2011) Research Advisor: Professor William F.DeGrado

Experience

  • Massachusetts Institute of Technology, Cambridge, MA U.S.A. Research Laboratory of Electronics and Department of Biology
  • Iberian Nanotechnology Laboratory(INL)
  • (September 2011-February 2013) Post-Doctoral Associate
  • LG Chem, Ltd, Daejeon Electronic Chemicals, Petrochemicals Research and Development
  • Assistant Professor (triple appointment) SKKU Advanced Institute of Nanotechnology, Department of Chemistry and Global Biomedical Engineering

Journal Article

  • (2021)  Sequence-dependent aggregation-prone conformations of islet amyloid polypeptide.  PHYSICAL CHEMISTRY CHEMICAL PHYSICS.  23,  39
  • (2020)  Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus.  VIRUSES-BASEL.  12,  9
  • (2020)  Evaluation of Cell-Penetrating Peptides Using Microfluidic In Vitro 3D Brain Endothelial Barrier.  MACROMOLECULAR BIOSCIENCE.  20,  6
  • (2020)  Supramolecular Peptide Hydrogel-Based Soft Neural Interface Augments Brain Signals through a Three-Dimensional Electrical Network.  ACS NANO.  14,  1
  • (2019)  Lipopeptide-Based Nanosome-Mediated Delivery of Hyperaccurate CRISPR/Cas9 Ribonucleoprotein for Gene Editing.  SMALL.  15,  46
  • (2019)  Bioengineered Short Carbon Nanotubes as Tumor-Targeted Carriers for Biomedical Imaging.  MACROMOLECULAR RESEARCH.  27,  8
  • (2019)  Small, Clickable, and Monovalent Magnetofluorescent Nanoparticles Enable Mechanogenetic Regulation of Receptors in a Crowded Live-Cell Microenvironment.  NANO LETTERS.  19,  6
  • (2019)  Surface-Controlled Molecular Self-Alignment in Polymer Actuators for Flexible Microrobot Applications.  POLYMERS.  11,  4
  • (2019)  Application of microwave-irradiation technique in deglycosylation of ginsenosides for improving apoptosis induction in human melanoma SK-MEL-2 cells.  BIOORGANIC & MEDICINAL CHEMISTRY LETTERS.  29,  3
  • (2019)  Virucidal nano-perforator of viral membrane trapping viral RNAs in the endosome.  NATURE COMMUNICATIONS.  10, 
  • (2018)  Single-Chain Atomic Crystals as Extracellular Matrix-Mimicking Material with Exceptional Biocompatibility and Bioactivity.  NANO LETTERS.  18,  12
  • (2018)  Natalenamides A-C, Cyclic Tripeptides from the Termite-Associated Actinomadura sp RB99.  MOLECULES.  23,  11
  • (2018)  Peptide-Programmable Nanoparticle Superstructures with Tailored Electrocatalytic Activity.  ACS NANO.  12,  7
  • (2018)  Correlation between the hierarchical structures and nanomechanical properties of amyloid fibrils.  NANOTECHNOLOGY.  29,  29
  • (2017)  Nature-Inspired Construction of Two-Dimensionally Self-Assembled Peptide on Pristine Graphene.  JOURNAL OF PHYSICAL CHEMISTRY LETTERS.  8,  16
  • (2017)  Enhancement of catalytic activity of a programmed gold nanoparticle superstructure modulated by supramolecular protein assembly.  CATALYSIS TODAY.  295,  Special SI
  • (2017)  Highly sensitive graphene biosensor by monomolecular self-assembly of receptors on graphene surface.  APPLIED PHYSICS LETTERS.  110,  20
  • (2017)  An injectable collagen/poly(gamma-glutamic acid) hydrogel as a scaffold of stem cells and alpha-lipoic acid for enhanced protection against renal dysfunction.  BIOMATERIALS SCIENCE.  5,  2
  • (2017)  Molecular characterization of a single-chain antibody variable fragment (scFv) specific for PspA from Streptococcus pneumoniae.  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.  482,  1
  • (2016)  Peptide-based bimetallic nanostructures with tailored surface compositions and their oxygen electroreduction activities.  CRYSTENGCOMM.  18,  32

Patent/Intellectual Property

  • 개선된 안정성을 갖는 핵산 분자 및 이의 용도.  10-2020-0067831.  20210526.  KOREA, REPUBLIC OF
  • 신규한 세포-투과 펩타이드 및 이를 포함하는 피부 개선용 조성물.  10-2020-0055044.  20210119.  KOREA, REPUBLIC OF
  • 생체적합성 전도성 단백질 젤을 포함하는 생체 신호 측정 및 생체 자극용 조성물(COMPOSITION FOR BIO-SIGNAL MEASUREMENT AND STIMULATION CONTAINING BIOCOMPATIBLE CONDUCTIVE PROTEIN GEL).  10-2017-0116637.  20200907.  KOREA, REPUBLIC OF
  • 나노 복합체 및 나노 복합체를 포함하는 분산액의 제조 방법(NANO COMPOSITE AND MANUFACTURING METHOD FOR DISPERSION INCLUDING THE NANO COMPOSITE).  10-2135-2210000.  20200713.  KOREA, REPUBLIC OF
  • 그래핀 및 단백질을 이용한 바이오센서 플랫폼의 제조방법, 이에 따라 제조된 바이오센서 플랫폼, 및 이를 포함하는 전계 효과 트랜지스터형 바이오센서.  10-2015-0154991.  20171110.  KOREA, REPUBLIC OF
  • 코일드 코일 단백질 및 그의 용도(COILED COIL PROTEIN AND USE THEREOF).  10-1798-7470000.  20171109.  KOREA, REPUBLIC OF
  • Biocompatable protein, biocompatible protein gel and biocompatible conductive protein gel comprising the protein and method for preparing the same.  14811350.  20170516.  UNITED STATES
  • 생체적합성 단백질, 이를 포함하는 생체 적합성 단백질 젤과 전도성 단백질 젤 및 그의 제조방법.  10-2015-0016171.  20150901.  KOREA, REPUBLIC OF

Honors / Awards

  • CERTIFICATE OF PATENT : BIOCOMPATIBLE PROTEIN, BIOCOMPATIBLE PROTEIN GEL AND BIOCOMPATIBLE CONDUCTIVE PROTEIN GEL COMPRISING THE PROTEIN AND PREPARING METHOD THEREOF(Patent Number:10-1551143)
  • CERTIFICATE OF PATENT : Design of peptides to develop new type of anti-body probe