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- Professor Kim In Su's research team publishes a paper in 'Angewandte Chemie'
- A research team led by Professor Kim In-Su at the School of Pharmacy of Sungkyunkwan University has developed a synthetic methodology to selectively transform nucleoside analogs, known as the core structure of antiviral drugs. The findings were published in the September issue of the online edition of Angewandte Chemie (IF = 12.959), a world-renowned journal in the field of chemistry. A nucleoside analog is a compound that is designed with an aim to resemble a structural unit of DNA or RNA by modifying the sugar or base which are the basic units of DNA and RNA. Due to inherent characteristics of nucleoside analogs, they could be absorbed into viral cells and control genomic synthesis and so could be used as an antiviral drug. So far, more than 20 nucleoside analogs have been used to treat various viral infections such as Herpes (HSV), AIDS (HIV), and hepatitis B/C (HBV/HCV). In particular, Remdesivir, which is in the spotlight as new COVID-19 treatment, is also known to contain a nucleoside analog. In this study, Professor Kim In-Su's research team developed the first synthetic method for selective alkylation of a nucleobase in nucleoside analogue by utilizing easily available sulfur ylide. Previously reported alkylation methods of nucleobase require organic solvents and complex processes involving multiple steps with low chemical reactivity, in turn, resulting in additional production costs and limitations for application in the pharmaceutical industry. Sulfur ylide is a reagent developed in 1960 by Nobel Prize-winning professor E. J. Corey, which has been used only in the manufacture of trigonal cyclic compounds. Professor Kim In-Su's research team has created an opportunity to showcase the importance of sulfur ylide as an effective reagent to alkylate nucleoside analogs. In this newly developed synthetic method, water or alcohol is used as a reaction solvent that is considered as environmentally green and can largely reduce the production cost. Professor Kim In-Su said, "The results are new discovery of the reactivity of sulfur ylides for direct functionalization of carbon-hydrogen bonds. In particular, the study has presented a new signal to aid the development of antiviral drugs for human suffering from the new viral infection, and can drastically improve the manufacturing method for nucleoside alkylation compared to the existing multi-stage synthetic process." The research was supported by Basic Research Laboratory Program (BRL), Mid-career Researcher Program and Original Bio & Medical Technology Development Program, funded by the National Research Foundation of Korea and the Ministry of Science and ICT (MSIT).
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- 작성일 2021-07-15
- 조회수 3148
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- Professor Shin Ju-Young's research team wins Ronald D. Mann Best Paper Award
- Professor Shin Joo-young's team won the Ronald D. Mann Best Paper Award from the Journal of Pharmacoepidemiology and Drug Safety(PDS). PDS has recognized an annual Best Paper Award for the strongest contribution in a given volume, as determined by the Editors and a representative from ISPE, since 2001. Professor Shin Joo-young's research team was selected from more than 350 papers published in 2019 and was honored to be the first Korean researcher and the second in Asia to win the Honorable Mention. Paper: An empirical assessment of immeasurable time bias in the setting of nested case-control studies: Statins and all-cause mortality among patients with heart failure
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- 작성일 2021-07-13
- 조회수 3079
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- School of Pharmacy welcomes Professor Lee Hyo-Jong
- Professor Lee Hyo-Jong is appointed to School of Pharmacy, SKKU as of September 1, 2020. Professor Lee Hyo-Jong earned a bachelor's degree ('98') from Sungkyunkwan University School of Pharmacy and a doctorate from Seoul National University. After earning his doctorate degree, he is a postdoctoral researcher at the University of Texas, M.D. Anderson Cancer Center, and has been working at Inje University School of Medicine since 2011. He has been appointed as an associate professor of this school since September 1st this year and will be in charge of teaching pathophysiology. We are very happy to have a great professor for the new semester, and we sincerely congratulate you on your appointment.
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- 작성일 2021-07-13
- 조회수 3097
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- Professor Shin Ju-Young's research team publishes a paper in Allergy
- Professor Shin Ju-Young, Dr. Lee Hyesung (co-author), and Kim Ju-Hwan (co-author, doctoral course) published their research on the incidence of anaphylaxis after vaccination among children in Korea in the journal of Allergy, a world-renowned journal in the field of allergy, on August 13. Paper: Anaphylaxis following vaccination among children in Asia: A large-linked database study
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- 작성일 2021-07-13
- 조회수 3171
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- SKKU School of Pharmacy signs MOU with Yonsei Univ. College of Pharmacy
- On August 8, the Graduate School of Pharmaceutical Industry Specialization at Woori University and the Graduate School of Pharmaceutical Industry Specialization at Yonsei University signed an MOU to develop and operate a Korean NIBRT program to foster core professionals in the bio-fair workforce. Professor Lee Sang-won, head of the Pharmaceutical Industry Specialization Graduate School of Sungkyunkwan University, Han Jung-hwan, head of Yonsei University's Pharmaceutical Industry Specialization Graduate School, Han Kyun-hee, and working-level staff attended the signing ceremony. Through this agreement, the two organizations will cooperate in developing and operating Korean-style NIBRT programs, developing and operating field education programs (undergraduate/graduate school), and pharmaceutical bio pharmaceutical research and development programs.
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- 작성일 2021-07-13
- 조회수 3053
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- Professor Han Jeung Whan, Research Professor Yi Sang Ah publishes a paper in 'Cell Death and Differentiation'
- Professor Han Jeung Whan (corresponding author) and Professor Yi Sang Ah (first author) has identified the specific epigenetic mechanism of developing cervical cancer by the human papilloma virus (HPV) and has published it in the journal 'Cell Death and Differentiation' (IF 10.717).
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- 작성일 2021-07-08
- 조회수 3023
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- Professor Shin Ju-young's research team publishes a paper in 'Clinical Infectious Disease'
- Professor Shin Ju-young, Dr. Jeong Han Eol, and Dr. Lee Hyesung (co-authors) published a study on the risk of nonsteroidal anti-inflammatory drugs (NSAIDs) among patients hospitalized with COVID-19 on July 27, 2020 in the journal 'Clinical Infectious Diseases' (IF 8.313, JCR ranking Top 3.2%). Title: "Association between NSAIDs use and adverse clinical outcomes among adults hospitalized with COVID-19 in South Korea: A nationwide study"
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- 작성일 2021-07-08
- 조회수 3055
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- School of Pharmacy Student President Moon Kyung Won donates 1 million won to Pharmacy Research Scholarship Fund
- Moon Kyung Won (Pharmacy, 16) donated a million won to the Research Scholarship Foundation for his alma mater. Moon Kyung Won, the current chairman of the 36th School of Pharmacy Student Council, Pholaris, has managed the student council under the motto of constant communication with students, better college life, and pleasant pharmacy, and has dedicated himself to the development of the School of Pharmacy.
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- 작성일 2021-07-08
- 조회수 3059
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- Professor Chung Kyu Hyuck, Dean of Graduate School, awarded as Medical & Pharmaceutical Affairs Columnists
- Professor Chung Kyu Hyuck, Dean of Graduate School was awarded as 43rd Medical & Pharmaceutical Affairs Columnists on June 29, 2020. Medical News · Daily Bosa has recently appointed this year’s Medical & Pharmaceutical Affairs Columnists recommendation committee (Chairman Han Kwang-soo, The Korea Society of columnists for medical & pharmaceutical affairs) to select six medical and pharmaceutical field opinion leaders. (Four awardees from medicine, two awardees from pharmacy) Professor Chung Kyu Hyuck has been announced as Pharmaceutical columnist along with Professor Oh Jung Mi of College of Pharmacy, Seoul National University. The Medical & Pharmaceutical Affairs Columnists recommendation was established in 1976 and is sponsored by JW Pharmaceutical.
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- 작성일 2021-07-06
- 조회수 3133
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- National Research Foundation funds Professor Jeong Ji Hoon’s team for Basic Research Laboratory (BRL) program
- Professor Jeong Ji Hoon’s team has been selected for Basic Research Laboratory (BRL) program funded by the National Research Foundation. The program funds 500 million won per year from July 2020 to February 2023. The project supports Professor Jeong and his team to develop “Innovative polar tissue interface regenerative supporter device technology”
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- 작성일 2021-07-06
- 조회수 3122