Professor Lee Eui-Kyung's research team and Professor Shin Ju-Young publishes a paper in 'JACI: in practice'
- 약학대학
- Hit3146
- 2021-08-03
Professor Lee Eui-Kyung's research team and Professor Shin Ju-Young published their cost-effectiveness evaluation on use of tiotropium in elderly patients with severe asthma in Journal of Allergy and Clinical Immunology-In Practice (JACI: in practice, IF = 7.574), a third leading journal in the field of allergy, on December 7th, 2020.
The team utilized database obtained from the Health Insurance Review and Assessment Service(HIRA) and confirmed that addition of tiotropium to ICS/LABA for elderly patients with severe asthma reduced the risk of asthman exacerbation. Elderly patients with severe asthma are usually excluded from randomized clinical trails(RCTs) due to comorbidities and multiple drug use. Following the thesis, they conducted a cost-effectiveness evaluation and concluded that the addition of tiotropium shows a higher cost-effectiveenss profile.
These results using real-world evidence provide information beyond the clinical outcomes reported by randomized controlled trials, providing a complementary ground in establishing the reimbursement criteria of tiotropium for elderly patients with severe asthma.
Title: Cost-effectiveness of tiotropium in elderly patients with severe asthma using real-world data