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Biohealth Regulatory Science

For more details on the courses, please refer to the Course Catalog

교육과정
Code Course Title Credit Learning Time Division Degree Grade Note Language Availability
BTH5076 Basic Natural Product Chemical Biology 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
- Students will understand basic natural product chemical biology related to microbiome. - Students will be able to improve their research ability through this class.
BTH5077 Advanced biopharmaceutical development 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
[Purpose of subject] - To introduce the latest biopharmaceuticals, and to educate the basic knowledge necessary for innovative bio-drug by understanding the entire process from basic research to the actual development of bio-drug. Through this education, we aim to train experts who can lead a paradigm change of biopharmaceutical development. [Main contents of subject] - Definition of biopharmaceuticals - Latest biopharmaceutical trend analysis - Principle and application of antibody drug development - Introduction of the development process of gene therapy - Principle and development of cell therapy - Discuss the problems of biopharmaceuticals developmenet
BTH5078 Methods in Computational Biology - Intermediate 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Since the entire human genome was first sequenced in the early 2000, a vast amount of diverse molecular profiles (i.e. DNA, RNA) have been generated from patients over multiple diseases. With the development of computer hardware and software technology necessary for analyzing these molecular data and the growing demand for personalized medicine and treatment, clinical and therapeutic studies using the molecular data have been rapidly increasing, and a huge number of data analysis methods have been introduced. For example, google scholar search with “gene feature selection” which is frequently employed in gene expression based studies outputs ~2,320,000 publications. This course is designed to introduce computational methods to graduate students in biomedical science and related disciplines. I expected students will have no to limited previous knowledge in computational biology. This course covers the most common methods in the field from their fundamental concepts to their practical applications. The completion of this course provides foundational knowledge in reproducible computational analysis and enables students to continue learning relevant tools to suit your research interests in computational biology.
BTH5079 Cancer immunology and Immunotherapy 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Cancer is the leading cause of death for Korean. So far, various cancer therapy has been developed. However, some anti-cancer drugs can interfere the cellular functions of fast-proliferating normal cells, thereby inducing harmful side-effect, while cancer may acquire the resistance for anti-cancer drugs by altering their genetic, epigenetic, and metabolic programs. Therefore, there’s been continuous unmet need for developing new anti-cancer therapy. Recently, cancer immunotherapy which harness patients’ intrinsic ability of immune system to eliminate cancer has been emerging, and has replaced or complemented the conventional cancer therapy. The aim of this lecture is understanding cancer cell-intrinsic, -extrinsic mechanisms to avoid immune attack, main players for cancer surveillance and their functions, complex interactions among immune cells, cancer cells and tumor microenvironmental factors and discuss diverse new developmental strategies for cancer immunotherapy.
BTH5080 Next generation organic molecule structure elucidation 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
With the development of various analytical techniques, it is essential to acquire knowledge about new organic compound analysis methods and to understand practical application techniques. In this course, lectures will be given on a wide range of techniques, from NMR, MS, UV, and IR, which are traditional methods for chemical structure identification of natural and synthetic organic compounds, to Microcrystal electron diffraction (MicroED), a state-of-the-art structure determination technique.
BTH5081 Microbial metabolic chemistry 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Microbial metabolites play an important role as lead compounds for new drugs. Biosynthesis studies of microbial metabolites have recently been active. In this course, lectures will be given on the knowledge and techniques of genes, proteins, biosynthetic precursors, and chemical reactions related to microbial metabolites.
BTH5082 Advanced Biotechnology I 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
In this class, students will give presentation related to their research work and future research direction and receive comments, feedbacks and advice from both audience (peer-students) and professors. Therefore, participants will not only learn the skills how to deliver their research work efficiently to audience, but also expand their knowledge for research topics (such as gene expression, central dogma, protein synthesis, and cell divisions, required for the processes of development, maturation, proliferation, differentiation and cross-regulation of such phenomena) and state-of-art biotechnologies from other students. In particular, for the purpose, recently published articles and reviews in biotechnology fields will be presented and discussed at the levels of molecular and cellular aspects.
BTH5083 Advanced Biotechnology II 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
In this class, students will give presentation related to their research work and future research direction and receive comments, feedbacks and advice from both audience (peer-students) and professors. Therefore, participants will not only learn the skills how to deliver their research work efficiently to audience, but also expand their knowledge for research topics (such as gene expression, central dogma, protein synthesis, and cell divisions, required for the processes of development, maturation, proliferation, differentiation and cross-regulation of such phenomena) and state-of-art biotechnologies from other students. In particular, for the purpose, recently published articles and reviews in biotechnology fields will be presented and discussed at the levels of molecular and cellular aspects.
BTH5084 Advanced Neurobiology 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Neurobiology is the scientific study of the nervous system. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, computer science and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The main theme of the lecture is to understand brain function and behavior. The lecture covers structure and function of the systems that serve the senses and command movements, andcomplex cognitive behaviors including motivation, mood, emotion, sleep, language, attention, and consciousness.
BTH5085 Advanced Cell Differentiation 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Cellular differentiation is the process in which a cell changes from one cell type to another. Usually, the cell changes to a more specialized type. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. This course covers several aspects of cellular differentiation in various organisms at molecular, cellular and whole animal body levels. Students are required to review and discuss papers on the special topics related to cell differentiation biology.
BTH5086 Advanced Biotechnology 1 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Biotechnology is technology that utilizes biological systems, living organisms or parts of this to develop or create different products. With the development of genetic engineering in the 1970s, research in biotechnology (and other related areas such as medicine, biology etc.) developed rapidly because of the new possibility to make changes in the organisms' genetic material (DNA). Today, biotechnology covers many different disciplines (eg. genetics, biochemistry, molecular biology, etc.). Through this lecture, students present to other students the research topics and progress they are conducting in the laboratory during their master's or doctoral degree programs.
BTH5087 Advanced Biotechnology 2 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Biotechnology is technology that utilizes biological systems, living organisms or parts of this to develop or create different products. With the development of genetic engineering in the 1970s, research in biotechnology (and other related areas such as medicine, biology etc.) developed rapidly because of the new possibility to make changes in the organisms' genetic material (DNA). Today, biotechnology covers many different disciplines (eg. genetics, biochemistry, molecular biology, etc.). Through this lecture, students present to other students the research topics and progress they are conducting in the laboratory during their master's or doctoral degree programs.
BTH5088 Introduction to Computational Biology 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Computational Biology is driving the collection and analysis of biomedical big data. This course is designed for the graduate students majoring in bioscience and provides a hands-on introduction to the computer-based analysis of genomic and biomolecular data. Students who are interested in taking Advanced Computational Biology are required to take this course. Students completing this course will be able to evaluate new genomic and biomolecular information using existing software and gain experience in combining bioinformatic approaches to answer specific biological questions.
BTH5089 Introduction to Tissue Engineering 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
Tissue engineering holds a great promise for noveldrug development and regenerative medicine. This course will cover the basic principlesof tissue development and regeneration, and engineering strategies to createhuman tissues and organs outside human body. The basic molecular/cellularmechanisms underlying embryogenesis, tissue morphogenesis, and tissueregeneration will be discussed. Students will learn design criteria for selectingbiomaterial scaffolds, cell sources, and soluble regulators, and engineeringstrategies for mimicking biophysical and biochemical cues. Select topicsinclude stem cells, organoids, and biomaterials. Examples of recent advancementof tissue engineering products will be discussed through recent case studies.
BTH5090 3D Bioprinting in Pharmaceutical Industry 3 6 Major Master/Doctor Biopharmaceutical Convergence - No
3D bioprinting is a form of additive manufacturing that usescells, biomaterials, and biological factors, known as bioinks, to print livingstructures. 3D bioprinting has the potential to revolutionize thepharmaceutical industry from drug screening to development of new class ofdrugs such as gene/cell-based therapy. This course will cover fundamental conceptsand engineering techniques essential for 3D bioprinting, basic understanding ofbiomaterials and key applications in pharmaceutical industry. The course willbe comprised of lecture, journal club, and lab components. Students will learnto 1) perform literature search and critical scientific reading in this emergingfield, 2) be equipped with foundational skills in 3D bioprinting workflow andbioink design, and 3) gain multidisciplinary skills such as utilizing CAD/slicingprograms, optimizing printing parameters, and designing materials propertiesfor various bioprinting applications.