Prof. Woo-Jae Jung, developed a bioinspired approach to create collagen-like materials
- Biotech.
- Hit2246
- 2016-10-24
Prof. Woo-Jae Jung, developed a bioinspired approach to create
collagen-like materials
Prof. Woo-Jae Jung research team published thesis 'Biomimetic Self-Templated Hierarchical Structures of Collagen-Like Peptide Amphiphiles' on 'Nano Letters'. (*URL: http://pubs.acs.org/doi/full/10.1021/acs.nanolett.5b03313)
The research team developed a bioinspired approach to create collagen-like materials through directed evolutionary screening and directed self-assembly.
Collagen is major structural protein that consists of human body. It constitutes hard tissue like bone or flexible tissue like skin in accordance of the way the molecule is systematized and make organization. Using this principle, Collagen maintains essential function by modulating biochemical features and mechanical property of various tissues; for example, bone, skin, tendon, ligament, cornea and so on. The main cause that various tissues consisting of same molecules show different features has been recognized that it is due to 'hierarchical structure, but it was difficult to represent the structure because of technical limitation. Also, there has been limitation on application of Collagen copying materials because of that reason.
Prof. Woo-Jae Jung research team succeeded in representing various imitating structures of body by developing the method that concentrates Collagen-like Peptide and induces molecular assembly phenomenon, and then stacks up sequentially various structures created in solution.
The result of the research is expected to contribute to development of next generation body materials and the other areas.